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Antibody-drug conjugates: recent advances in conjugation and linker chemistries
The antibody-drug conjugate (ADC), a humanized or human monoclonal antibody conjugated with highly cytotoxic small molecules (payloads) through chemical linkers, is a novel therapeutic format and has great potential to make a paradigm shift in cancer chemotherapy. This new antibody-based molecular p...
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| Veröffentlicht in: | Protein Cell |
|---|---|
| Hauptverfasser: | , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Higher Education Press
2016
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5777969/ https://ncbi.nlm.nih.gov/pubmed/27743348 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s13238-016-0323-0 |
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