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Recent advances in the development of anti-HER2 antibodies and antibody-drug conjugates

Human epidermal growth factor receptor 2 (HER2)-targeted therapies have revolutionized the treatment of HER2-positive breast cancer, both in the metastatic and early stage settings. While trastuzumab and lapatinib had been the mainstays of treatment in combination with chemotherapy, innate and acqui...

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Detalhes bibliográficos
Publicado no:Ann Transl Med
Main Authors: Wong, Deborah J.L., Hurvitz, Sara A.
Formato: Artigo
Idioma:Inglês
Publicado em: AME Publishing Company 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4260046/
https://ncbi.nlm.nih.gov/pubmed/25568875
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3978/j.issn.2305-5839.2014.08.13
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