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Antibody Drug Conjugates: Design and Selection of Linker, Payload and Conjugation Chemistry

Antibody drug conjugates (ADCs) have emerged as an important pharmaceutical class of drugs designed to harness the specificity of antibodies with the potency of small molecule therapeutics. The three main components of ADCs are the antibody, the linker, and the payload; the majority of early work fo...

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書目詳細資料
發表在:AAPS J
Main Authors: McCombs, Jessica R., Owen, Shawn C.
格式: Artigo
語言:Inglês
出版: Springer US 2015
主題:
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4365093/
https://ncbi.nlm.nih.gov/pubmed/25604608
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1208/s12248-014-9710-8
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