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Preclinical Pharmacokinetic Considerations for the Development of Antibody Drug Conjugates

Antibody drug conjugates (ADCs) are an emerging new class of targeted therapeutics for cancer that use antibodies to deliver cytotoxic drugs to cancer cells. There are two FDA approved ADCs on the market and over 30 ADCs in the clinical pipeline against a number of different cancer types. The struct...

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Podrobná bibliografie
Vydáno v:Pharm Res
Hlavní autoři: Kamath, Amrita V., Iyer, Suhasini
Médium: Artigo
Jazyk:Inglês
Vydáno: Springer US 2014
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4596897/
https://ncbi.nlm.nih.gov/pubmed/25446773
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11095-014-1584-z
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