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Preclinical Pharmacokinetic Considerations for the Development of Antibody Drug Conjugates

Antibody drug conjugates (ADCs) are an emerging new class of targeted therapeutics for cancer that use antibodies to deliver cytotoxic drugs to cancer cells. There are two FDA approved ADCs on the market and over 30 ADCs in the clinical pipeline against a number of different cancer types. The struct...

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Kaydedildi:
Detaylı Bibliyografya
Yayımlandı:Pharm Res
Asıl Yazarlar: Kamath, Amrita V., Iyer, Suhasini
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Springer US 2014
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4596897/
https://ncbi.nlm.nih.gov/pubmed/25446773
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11095-014-1584-z
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