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Synthesis and study of new paramagnetic and diamagnetic verapamil derivatives

New derivatives of verapamil (1) modified with nitroxides and their precursors were synthesized and screened for reactive oxygen species (ROS) scavenging activities. The basic structure was modified by changing the nitrile group to an amide or the methyl substituent on tertiary nitrogen with nitroxi...

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Detalhes bibliográficos
Publicado no:Bioorg Med Chem
Main Authors: Bognár, Balázs, Ahmed, Shabnam, Kuppusamy, M. Lakshmi, Selvendiran, Karuppaiyah, Khan, Mahmood, Jekő, József, Hankovszky, Olga H., Kálai, Tamás, Kuppusamy, Periannan, Hideg, Kálmán
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4596527/
https://ncbi.nlm.nih.gov/pubmed/20347319
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmc.2010.02.040
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