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Synthesis and study of new paramagnetic and diamagnetic verapamil derivatives
New derivatives of verapamil (1) modified with nitroxides and their precursors were synthesized and screened for reactive oxygen species (ROS) scavenging activities. The basic structure was modified by changing the nitrile group to an amide or the methyl substituent on tertiary nitrogen with nitroxi...
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Publicado no: | Bioorg Med Chem |
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Main Authors: | , , , , , , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2010
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4596527/ https://ncbi.nlm.nih.gov/pubmed/20347319 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmc.2010.02.040 |
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