Amelioration of Doxorubicin-Induced Cardiotoxicity by an Anticancer-Antioxidant Dual-Function Compound, HO-3867

Doxorubicin (DOX) is a drug commonly used for the treatment of cancer. The development of resistance to DOX is common, and high cumulative doses cause potentially lethal cardiac side effects. HO-3867 (3,5-bis(4-fluorobenzylidene)-1-[(2,2,5,5-tetramethyl-2,5-dihydro-1-hydroxy-pyrrol-3-yl)methyl]piper...

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Detalhes bibliográficos
Main Authors: Dayton, Alex, Selvendiran, Karuppaiyah, Meduru, Sarath, Khan, Mahmood, Kuppusamy, M. Lakshmi, Naidu, Shan, Kálai, Tamás, Hideg, Kálmán, Kuppusamy, Periannan
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Pharmacology and Experimental Therapeutics 2011
Assuntos:
Cardiovascular
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3199994/
https://ncbi.nlm.nih.gov/pubmed/21799049
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/jpet.111.183681
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