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Cellular uptake, retention and bioabsorption of HO-3867, a fluorinated curcumin analog with potential antitumor properties

Curcumin, a naturally-occurring compound found in the rhizome of Curcuma longa plant, is known for its antitumor activities. However, its clinical efficacy is limited due to poor bioabsorption. A new class of synthetic analogs of curcumin, namely diarylidenylpiperidone (DAP), has been developed with...

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Detalhes bibliográficos
Main Authors: Dayton, Alex, Selvendiran, Karuppaiyah, Kuppusamy, M Lakshmi, Rivera, Brian K, Meduru, Sarath, Kálai, Tamás, Hideg, Kálmán, Kuppusamy, Periannan
Formato: Artigo
Idioma:Inglês
Publicado em: Landes Bioscience 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3047094/
https://ncbi.nlm.nih.gov/pubmed/20798598
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cbt.10.10.13250
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