HO-3867, a synthetic compound, inhibits migration and invasion of ovarian carcinoma cells through downregulation of fatty acid synthase and focal adhesion kinase

Fatty acid synthase (FAS) and focal adhesion kinase (FAK), which are overexpressed in a variety of human epithelial tumors, play a key role in the migration and invasion of cancer cells. Hence, strategies targeted at inhibiting the FAS/FAK proteins may have therapeutic potential for cancer treatment...

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Main Authors: Selvendiran, Karuppaiyah, Ahmed, Shabnam, Dayton, Alex, Ravi, Yazhini, Kuppusamy, M. Lakshmi, Bratasz, Anna, Rivera, Brian K., Kálai, Tamás, Hideg, Kálmán, Kuppusamy, Periannan
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2010
Ábhair:
Article
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2941821/
https://ncbi.nlm.nih.gov/pubmed/20713491
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1541-7786.MCR-10-0201
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