HO-3867, a synthetic compound, inhibits migration and invasion of ovarian carcinoma cells through downregulation of fatty acid synthase and focal adhesion kinase

Fatty acid synthase (FAS) and focal adhesion kinase (FAK), which are overexpressed in a variety of human epithelial tumors, play a key role in the migration and invasion of cancer cells. Hence, strategies targeted at inhibiting the FAS/FAK proteins may have therapeutic potential for cancer treatment...

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Detalhes bibliográficos
Main Authors: Selvendiran, Karuppaiyah, Ahmed, Shabnam, Dayton, Alex, Ravi, Yazhini, Kuppusamy, M. Lakshmi, Bratasz, Anna, Rivera, Brian K., Kálai, Tamás, Hideg, Kálmán, Kuppusamy, Periannan
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2941821/
https://ncbi.nlm.nih.gov/pubmed/20713491
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1541-7786.MCR-10-0201
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