Synthesis and study of new paramagnetic and diamagnetic verapamil derivatives

New derivatives of verapamil (1) modified with nitroxides and their precursors were synthesized and screened for reactive oxygen species (ROS) scavenging activities. The basic structure was modified by changing the nitrile group to an amide or the methyl substituent on tertiary nitrogen with nitroxi...

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Bibliografske podrobnosti
izdano v:Bioorg Med Chem
Main Authors: Bognár, Balázs, Ahmed, Shabnam, Kuppusamy, M. Lakshmi, Selvendiran, Karuppaiyah, Khan, Mahmood, Jekő, József, Hankovszky, Olga H., Kálai, Tamás, Kuppusamy, Periannan, Hideg, Kálmán
Format: Artigo
Jezik:Inglês
Izdano: 2010
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4596527/
https://ncbi.nlm.nih.gov/pubmed/20347319
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmc.2010.02.040
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