Phase II study of PX-866 in recurrent glioblastoma

BACKGROUND: Glioblastoma (GBM) is the most aggressive malignancy of the central nervous system in adults. Increased activity of the phosphatidylinositol-3-OH kinase (PI3K) signal transduction pathway is common. We performed a phase II study using PX-866, an oral PI3K inhibitor, in participants with...

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Dades bibliogràfiques
Publicat a:Neuro Oncol
Autors principals: Pitz, Marshall W., Eisenhauer, Elizabeth A., MacNeil, Mary V., Thiessen, Brian, Easaw, Jacob C., Macdonald, David R., Eisenstat, David D., Kakumanu, Ankineedu S., Salim, Muhammad, Chalchal, Haji, Squire, Jeremy, Tsao, Ming Sound, Kamel-Reid, Suzanne, Banerji, Shantanu, Tu, Dongsheng, Powers, Jean, Hausman, Diana F., Mason, Warren P.
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2015
Matèries:
Clinical Investigations
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4588751/
https://ncbi.nlm.nih.gov/pubmed/25605819
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nou365
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