Phase II study of PX-866 in recurrent glioblastoma

BACKGROUND: Glioblastoma (GBM) is the most aggressive malignancy of the central nervous system in adults. Increased activity of the phosphatidylinositol-3-OH kinase (PI3K) signal transduction pathway is common. We performed a phase II study using PX-866, an oral PI3K inhibitor, in participants with...

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Foilsithe in:Neuro Oncol
Main Authors: Pitz, Marshall W., Eisenhauer, Elizabeth A., MacNeil, Mary V., Thiessen, Brian, Easaw, Jacob C., Macdonald, David R., Eisenstat, David D., Kakumanu, Ankineedu S., Salim, Muhammad, Chalchal, Haji, Squire, Jeremy, Tsao, Ming Sound, Kamel-Reid, Suzanne, Banerji, Shantanu, Tu, Dongsheng, Powers, Jean, Hausman, Diana F., Mason, Warren P.
Formáid: Artigo
Teanga:Inglês
Foilsithe: Oxford University Press 2015
Ábhair:
Clinical Investigations
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4588751/
https://ncbi.nlm.nih.gov/pubmed/25605819
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nou365
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