Φορτώνει......
Cellular and in vivo activity of a novel PI3K inhibitor, PX-866, against human glioblastoma
The phosphatidylinositol-3-kinase (PI3K)/Akt oncogenic pathway is critical in glioblastomas. Loss of PTEN, a negative regulator of the PI3K pathway or activated PI3K/Akt pathway that drive increased proliferation, survival, neovascularization, glycolysis, and invasion is found in 70%–80% of malignan...
Αποθηκεύτηκε σε:
| Κύριοι συγγραφείς: | , , , , , , , , , |
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| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
Oxford University Press
2010
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2940638/ https://ncbi.nlm.nih.gov/pubmed/20156803 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nop058 |
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