Combined action of the dinuclear platinum compound BBR3610 with the PI3-K inhibitor PX-866 in glioblastoma

Polynuclear platinum compounds are more effective at killing glioblastoma cells than cisplatin, work by a different mechanism, and typically do not induce high levels of apoptosis at early time points after exposure. Here we tested the hypothesis that combining BBR3610, the most potent polynuclear p...

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Main Authors: Gwak, Ho-Shin, Shingu, Takashi, Chumbalkar, Vaibhav, Hwang, Yeo-Hyeon, DeJournett, Robert, Latha, Khatri, Koul, Dimpy, Yung, W.K. Alfred, Powis, Garth, Farrell, Nicholas P., Bögler, Oliver
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2990813/
https://ncbi.nlm.nih.gov/pubmed/20473884
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ijc.25394
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