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Combined action of the dinuclear platinum compound BBR3610 with the PI3-K inhibitor PX-866 in glioblastoma
Polynuclear platinum compounds are more effective at killing glioblastoma cells than cisplatin, work by a different mechanism, and typically do not induce high levels of apoptosis at early time points after exposure. Here we tested the hypothesis that combining BBR3610, the most potent polynuclear p...
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| Main Authors: | , , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2990813/ https://ncbi.nlm.nih.gov/pubmed/20473884 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ijc.25394 |
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