Farnesoid X Receptor Inhibits Glucagon-Like Peptide-1 Production by Enteroendocrine L-cells

Bile acids (BA) are signalling molecules which activate the transmembrane receptor TGR5 and the nuclear receptor FXR. BA sequestrants (BAS) complex BA in the intestinal lumen and decrease intestinal FXR activity. The BAS-BA complex also induces Glucagon-Like Peptide-1 (GLP-1) production by L-cells w...

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Xehetasun bibliografikoak
Argitaratua izan da:Nat Commun
Egile Nagusiak: TRABELSI, Mohamed-Sami, DAOUDI, Mehdi, PRAWITT, Janne, DUCASTEL, Sarah, TOUCHE, Véronique, SAYIN, Sama I., PERINO, Alessia, BRIGHTON, Cheryl A., SEBTI, Yasmine, KLUZA, Jérôme, BRIAND, Olivier, DEHONDT, Hélène, VALLEZ, Emmanuelle, DORCHIES, Emilie, BAUD, Grégory, SPINELLI, Valeria, HENNUYER, Nathalie, CARON, Sandrine, BANTUBUNGI, Kadiombo, CAIAZZO, Robert, REIMANN, Frank, MARCHETTI, Philippe, LEFEBVRE, Philippe, BÄCKHED, Fredrik, GRIBBLE, Fiona M., SCHOONJANS, Kristina, PATTOU, François, TAILLEUX, Anne, STAELS, Bart, LESTAVEL, Sophie
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2015
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4579574/
https://ncbi.nlm.nih.gov/pubmed/26134028
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms8629
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