Farnesoid X Receptor Inhibits the Transcriptional Activity of Carbohydrate Response Element Binding Protein in Human Hepatocytes

The glucose-activated transcription factor carbohydrate response element binding protein (ChREBP) induces the expression of hepatic glycolytic and lipogenic genes. The farnesoid X receptor (FXR) is a nuclear bile acid receptor controlling bile acid, lipid, and glucose homeostasis. FXR negatively reg...

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Bibliografiske detaljer
Main Authors: Caron, Sandrine, Huaman Samanez, Carolina, Dehondt, Hélène, Ploton, Maheul, Briand, Olivier, Lien, Fleur, Dorchies, Emilie, Dumont, Julie, Postic, Catherine, Cariou, Bertrand, Lefebvre, Philippe, Staels, Bart
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2013
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Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3648076/
https://ncbi.nlm.nih.gov/pubmed/23530060
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.01004-12
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