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O-GlcNAcylation Links ChREBP and FXR to Glucose-Sensing
Accumulating evidence suggests that O-GlcNAc transferase, an enzyme responsible for O-GlcNAc post-translational modification acts as a nutrient sensor that links glucose and the hexosamine biosynthetic pathway to the regulation of transcriptional factors involved in energy homeostasis. In liver, glu...
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| Publicado no: | Front Endocrinol (Lausanne) |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Frontiers Media S.A.
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4292737/ https://ncbi.nlm.nih.gov/pubmed/25628602 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fendo.2014.00230 |
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