S6 Kinase- and β-TrCP2-Dependent Degradation of p19(Arf) Is Required for Cell Proliferation

The kinase mTOR (mammalian target of rapamycin) promotes translation as well as cell survival and proliferation under nutrient-rich conditions. Whereas mTOR activates translation through ribosomal protein S6 kinase (S6K) and eukaryotic translation initiation factor 4E-binding protein (4E-BP), how it...

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Bibliografiset tiedot
Julkaisussa:Mol Cell Biol
Päätekijät: Nakagawa, Tadashi, Araki, Takaaki, Nakagawa, Makiko, Hirao, Atsushi, Unno, Michiaki, Nakayama, Keiko
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Society for Microbiology 2015
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Articles
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4573705/
https://ncbi.nlm.nih.gov/pubmed/26240281
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00343-15
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