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Regulation of mitosis-meiosis transition by the ubiquitin ligase β-TrCP in male germ cells
The mitosis-meiosis transition is essential for spermatogenesis. Specific and timely downregulation of the transcription factor DMRT1, and consequent induction of Stra8 expression, is required for this process in mammals, but the molecular mechanism has remained unclear. Here, we show that β-TrCP, t...
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| Publicat a: | Development |
|---|---|
| Autors principals: | , , , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
The Company of Biologists Ltd
2017
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5719248/ https://ncbi.nlm.nih.gov/pubmed/28982686 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.158485 |
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