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Regulation of mitosis-meiosis transition by the ubiquitin ligase β-TrCP in male germ cells

The mitosis-meiosis transition is essential for spermatogenesis. Specific and timely downregulation of the transcription factor DMRT1, and consequent induction of Stra8 expression, is required for this process in mammals, but the molecular mechanism has remained unclear. Here, we show that β-TrCP, t...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Development
Prif Awduron: Nakagawa, Tadashi, Zhang, Teng, Kushi, Ryo, Nakano, Seiji, Endo, Takahiro, Nakagawa, Makiko, Yanagihara, Noriko, Zarkower, David, Nakayama, Keiko
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: The Company of Biologists Ltd 2017
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5719248/
https://ncbi.nlm.nih.gov/pubmed/28982686
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.158485
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