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Crumbs promotes expanded recognition and degradation by the SCF(Slimb/β-TrCP) ubiquitin ligase

In epithelial tissues, growth control depends on the maintenance of proper architecture through apicobasal polarity and cell–cell contacts. The Hippo signaling pathway has been proposed to sense tissue architecture and cell density via an intimate coupling with the polarity and cell contact machiner...

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Autori principali: Ribeiro, Paulo, Holder, Maxine, Frith, David, Snijders, Ambrosius P., Tapon, Nicolas
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2014
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4024906/
https://ncbi.nlm.nih.gov/pubmed/24778256
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1315508111
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