Crumbs promotes expanded recognition and degradation by the SCF(Slimb/β-TrCP) ubiquitin ligase

In epithelial tissues, growth control depends on the maintenance of proper architecture through apicobasal polarity and cell–cell contacts. The Hippo signaling pathway has been proposed to sense tissue architecture and cell density via an intimate coupling with the polarity and cell contact machiner...

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Bibliografiska uppgifter
Huvudupphovsmän: Ribeiro, Paulo, Holder, Maxine, Frith, David, Snijders, Ambrosius P., Tapon, Nicolas
Materialtyp: Artigo
Språk:Inglês
Publicerad: National Academy of Sciences 2014
Ämnen:
PNAS Plus
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4024906/
https://ncbi.nlm.nih.gov/pubmed/24778256
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1315508111
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