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Regulation of mitosis-meiosis transition by the ubiquitin ligase β-TrCP in male germ cells

The mitosis-meiosis transition is essential for spermatogenesis. Specific and timely downregulation of the transcription factor DMRT1, and consequent induction of Stra8 expression, is required for this process in mammals, but the molecular mechanism has remained unclear. Here, we show that β-TrCP, t...

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Bibliografski detalji
Izdano u:Development
Glavni autori: Nakagawa, Tadashi, Zhang, Teng, Kushi, Ryo, Nakano, Seiji, Endo, Takahiro, Nakagawa, Makiko, Yanagihara, Noriko, Zarkower, David, Nakayama, Keiko
Format: Artigo
Jezik:Inglês
Izdano: The Company of Biologists Ltd 2017
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5719248/
https://ncbi.nlm.nih.gov/pubmed/28982686
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.158485
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