Regulation of mitosis-meiosis transition by the ubiquitin ligase β-TrCP in male germ cells

The mitosis-meiosis transition is essential for spermatogenesis. Specific and timely downregulation of the transcription factor DMRT1, and consequent induction of Stra8 expression, is required for this process in mammals, but the molecular mechanism has remained unclear. Here, we show that β-TrCP, t...

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Dettagli Bibliografici
Pubblicato in:Development
Autori principali: Nakagawa, Tadashi, Zhang, Teng, Kushi, Ryo, Nakano, Seiji, Endo, Takahiro, Nakagawa, Makiko, Yanagihara, Noriko, Zarkower, David, Nakayama, Keiko
Natura: Artigo
Lingua:Inglês
Pubblicazione: The Company of Biologists Ltd 2017
Soggetti:
Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5719248/
https://ncbi.nlm.nih.gov/pubmed/28982686
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.158485
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