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S6 Kinase- and β-TrCP2-Dependent Degradation of p19(Arf) Is Required for Cell Proliferation
The kinase mTOR (mammalian target of rapamycin) promotes translation as well as cell survival and proliferation under nutrient-rich conditions. Whereas mTOR activates translation through ribosomal protein S6 kinase (S6K) and eukaryotic translation initiation factor 4E-binding protein (4E-BP), how it...
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| Gepubliceerd in: | Mol Cell Biol |
|---|---|
| Hoofdauteurs: | , , , , , |
| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
American Society for Microbiology
2015
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4573705/ https://ncbi.nlm.nih.gov/pubmed/26240281 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00343-15 |
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