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Mechanistic Analysis of Ghrelin-O-Acyltransferase Using Substrate Analogs
Ghrelin-O-Acyltransferase (GOAT) is an 11-transmembrane integral membrane protein that octanoylates the metabolism-regulating peptide hormone ghrelin at Ser3 and may represent an attractive target for the treatment of type II diabetes and the metabolic syndrome. Protein octanoylation is unique to gh...
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| 出版年: | Bioorg Chem |
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| 主要な著者: | , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2015
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4567917/ https://ncbi.nlm.nih.gov/pubmed/26246082 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bioorg.2015.07.003 |
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