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Mechanistic Analysis of Ghrelin-O-Acyltransferase Using Substrate Analogs
Ghrelin-O-Acyltransferase (GOAT) is an 11-transmembrane integral membrane protein that octanoylates the metabolism-regulating peptide hormone ghrelin at Ser3 and may represent an attractive target for the treatment of type II diabetes and the metabolic syndrome. Protein octanoylation is unique to gh...
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| Publicado no: | Bioorg Chem |
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| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4567917/ https://ncbi.nlm.nih.gov/pubmed/26246082 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bioorg.2015.07.003 |
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