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Architectural Organization of the Metabolic Regulatory Enzyme Ghrelin O-Acyltransferase
Ghrelin O-acyltransferase (GOAT) is a polytopic integral membrane protein required for activation of ghrelin, a secreted metabolism-regulating peptide hormone. Although GOAT is a potential therapeutic target for the treatment of obesity and diabetes and plays a key role in other physiologic processe...
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| Autori principali: | , , , , , , , , , , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
American Society for Biochemistry and Molecular Biology
2013
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3820860/ https://ncbi.nlm.nih.gov/pubmed/24045953 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.510313 |
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