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Ghrelin O-Acyltransferase Assays and Inhibition
Ghrelin O-acyltransferase (GOAT) is responsible for catalyzing the attachment of the eight-carbon fatty acid octanoyl to the Ser3 side chain of the peptide ghrelin to generate the active form of this metabolic hormone. As such, GOAT is viewed as a potential therapeutic target for the treatment of ob...
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| Autors principals: | , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2012
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3763810/ https://ncbi.nlm.nih.gov/pubmed/22975055 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/B978-0-12-381272-8.00013-1 |
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