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Ghrelin O-Acyltransferase Assays and Inhibition

Ghrelin O-acyltransferase (GOAT) is responsible for catalyzing the attachment of the eight-carbon fatty acid octanoyl to the Ser3 side chain of the peptide ghrelin to generate the active form of this metabolic hormone. As such, GOAT is viewed as a potential therapeutic target for the treatment of ob...

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Detalles Bibliográficos
Main Authors: Taylor, Martin S., Hwang, Yousang, Hsiao, Po-Yuan, Boeke, Jef D., Cole, Philip A.
Formato: Artigo
Idioma:Inglês
Publicado: 2012
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3763810/
https://ncbi.nlm.nih.gov/pubmed/22975055
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/B978-0-12-381272-8.00013-1
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