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Inhibition of ghrelin O-acyltransferase (GOAT) by octanoylated pentapeptides
The discovery of ghrelin O-acyltransferase (GOAT) opens the way to the design of drugs that block the attachment of an octanoyl group to the appetite-stimulating peptide hormone ghrelin, potentially preventing obesity. Here, we develop a biochemical assay that uses membranes from insect cells infect...
Gorde:
| Egile Nagusiak: | , , , |
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| Formatua: | Artigo |
| Hizkuntza: | Inglês |
| Argitaratua: |
National Academy of Sciences
2008
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| Gaiak: | |
| Sarrera elektronikoa: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2504781/ https://ncbi.nlm.nih.gov/pubmed/18669668 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0805353105 |
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