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Ghrelin octanoylation mediated by an orphan lipid transferase

The peptide hormone ghrelin is the only known protein modified with an O-linked octanoyl side group, which occurs on its third serine residue. This modification is crucial for ghrelin's physiological effects including regulation of feeding, adiposity, and insulin secretion. Despite the crucial...

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Detalhes bibliográficos
Main Authors: Gutierrez, Jesus A., Solenberg, Patricia J., Perkins, Douglas R., Willency, Jill A., Knierman, Michael D., Jin, Zhaoyan, Witcher, Derrick R., Luo, Shuang, Onyia, Jude E., Hale, John E.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2008
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2359796/
https://ncbi.nlm.nih.gov/pubmed/18443287
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0800708105
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