Notum deacylates octanoylated ghrelin

OBJECTIVES: The only proteins known to be modified by O-linked lipidation are Wnts and ghrelin, and enzymatic removal of this post-translational modification inhibits ligand activity. Indeed, the Wnt-deacylase activity of Notum is the basis of its ability to act as a feedback inhibitor of Wnt signal...

Descrición completa

Gardado en:
Detalles Bibliográficos
Publicado en:Mol Metab
Main Authors: Zhao, Yuguang, Schuhmacher, Laura-Nadine, Roberts, Morgan, Kakugawa, Satoshi, Bineva-Todd, Ganka, Howell, Steve, O'Reilly, Nicola, Perret, Christine, Snijders, Ambrosius P., Vincent, Jean-Paul, Jones, E. Yvonne
Formato: Artigo
Idioma:Inglês
Publicado: Elsevier 2021
Assuntos:
Brief Communication
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC8010218/
https://ncbi.nlm.nih.gov/pubmed/33647468
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molmet.2021.101201
Tags: Engadir etiqueta
Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!

Títulos similares