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Endogenous ghrelin-O-acyltransferase (GOAT) acylates local ghrelin in the hippocampus
Ghrelin is an appetite-stimulating peptide. Serine 3 on ghrelin must be acylated by octanoate via the enzyme ghrelin-O-acyltransferase (GOAT) for the peptide to bind and activate the cognate receptor, Growth hormone secretagogue receptor type 1a (GHSR1a). Interest in GHSR1a increased dramatically wh...
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| Publicado no: | J Neurochem |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5832437/ https://ncbi.nlm.nih.gov/pubmed/29063591 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jnc.14244 |
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