Caricamento...

Recent progress in the discovery of ghrelin O-acyltransferase (GOAT) inhibitors

Ghrelin is a stomach-derived peptide hormone which stimulates appetite. For ghrelin to exert its orexigenic effect, octanoylation on the serine-3 residue of this gut–brain peptide is essential. The octanoylation of ghrelin is mediated by a unique acyltransferase enzyme known as ghrelin O-acyltransfe...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Pubblicato in:RSC Med Chem
Autori principali: Iyer, Malliga R., Wood, Casey M., Kunos, George
Natura: Artigo
Lingua:Inglês
Pubblicazione: Royal Society of Chemistry 2020
Soggetti:
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7651998/
https://ncbi.nlm.nih.gov/pubmed/33479618
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/d0md00210k
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !