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PE and PS Lipids Synergistically Enhance Membrane Poration by a Peptide with Anticancer Properties
Polybia-MP1 (MP1) is a bioactive host-defense peptide with known anticancer properties. Its activity is attributed to excess serine (phosphatidylserine (PS)) on the outer leaflet of cancer cells. Recently, higher quantities of phosphatidylethanolamine (PE) were also found at these cells’ surface. We...
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| Publié dans: | Biophys J |
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| Auteurs principaux: | , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
The Biophysical Society
2015
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4564682/ https://ncbi.nlm.nih.gov/pubmed/26331251 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2015.07.033 |
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