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PH-Triggered, Macromolecule-Sized Poration of Lipid Bilayers by Synthetically Evolved Peptides

pH-triggered membrane permeabilizing peptides could be exploited in a variety of applications, such as to enable cargo release from endosomes for cellular delivery, or as cancer therapeutics that selectively permeabilize the plasma membranes of malignant cells. Such peptides would be especially usef...

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Dettagli Bibliografici
Pubblicato in:J Am Chem Soc
Autori principali: Wiedman, Gregory, Kim, Sarah Y., Zapata-Mercado, Elmer, Wimley, William C., Hristova, Kalina
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2017
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5521809/
https://ncbi.nlm.nih.gov/pubmed/28001058
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.6b11447
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