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PH-Triggered, Macromolecule-Sized Poration of Lipid Bilayers by Synthetically Evolved Peptides

pH-triggered membrane permeabilizing peptides could be exploited in a variety of applications, such as to enable cargo release from endosomes for cellular delivery, or as cancer therapeutics that selectively permeabilize the plasma membranes of malignant cells. Such peptides would be especially usef...

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Bibliografiske detaljer
Udgivet i:J Am Chem Soc
Main Authors: Wiedman, Gregory, Kim, Sarah Y., Zapata-Mercado, Elmer, Wimley, William C., Hristova, Kalina
Format: Artigo
Sprog:Inglês
Udgivet: 2017
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5521809/
https://ncbi.nlm.nih.gov/pubmed/28001058
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.6b11447
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