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Highly Efficient Macromolecule-Sized Poration of Lipid Bilayers by a Synthetically Evolved Peptide

[Image: see text] Peptides that self-assemble, at low concentration, into bilayer-spanning pores which allow the passage of macromolecules would be beneficial in multiple areas of biotechnology. However, there are few, if any, natural or designed peptides that have this property. Here we show that t...

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Detalhes bibliográficos
Main Authors: Wiedman, Gregory, Fuselier, Taylor, He, Jing, Searson, Peter C., Hristova, Kalina, Wimley, William C.
Formato: Artigo
Idioma:Inglês
Publicado em: American Chemical Society 2014
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3985440/
https://ncbi.nlm.nih.gov/pubmed/24588399
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja500462s
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