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PH-Triggered, Macromolecule-Sized Poration of Lipid Bilayers by Synthetically Evolved Peptides

pH-triggered membrane permeabilizing peptides could be exploited in a variety of applications, such as to enable cargo release from endosomes for cellular delivery, or as cancer therapeutics that selectively permeabilize the plasma membranes of malignant cells. Such peptides would be especially usef...

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Bibliografiska uppgifter
I publikationen:J Am Chem Soc
Huvudupphovsmän: Wiedman, Gregory, Kim, Sarah Y., Zapata-Mercado, Elmer, Wimley, William C., Hristova, Kalina
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2017
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5521809/
https://ncbi.nlm.nih.gov/pubmed/28001058
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.6b11447
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