PE and PS Lipids Synergistically Enhance Membrane Poration by a Peptide with Anticancer Properties

Polybia-MP1 (MP1) is a bioactive host-defense peptide with known anticancer properties. Its activity is attributed to excess serine (phosphatidylserine (PS)) on the outer leaflet of cancer cells. Recently, higher quantities of phosphatidylethanolamine (PE) were also found at these cells’ surface. We...

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Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Biophys J
Egile Nagusiak: Leite, Natália Bueno, Aufderhorst-Roberts, Anders, Palma, Mario Sergio, Connell, Simon D., Neto, João Ruggiero, Beales, Paul A.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: The Biophysical Society 2015
Gaiak:
Membranes
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4564682/
https://ncbi.nlm.nih.gov/pubmed/26331251
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2015.07.033
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