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Synergistic Anticancer Effects of the 9.2.27PE Immunotoxin and ABT-737 in Melanoma

In cancer, combinations of drugs targeting different cellular functions is well accepted to improve tumor control. We studied the effects of a Pseudomonas exotoxin A (PE) - based immunotoxin, the 9.2.27PE, and the BH-3 mimetic compound ABT-737 in a panel of melanoma cell lines. The drug combination...

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Autors principals: Risberg, Karianne, Fodstad, Øystein, Andersson, Yvonne
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2011
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3168478/
https://ncbi.nlm.nih.gov/pubmed/21915275
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0024012
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