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The MOC31PE immunotoxin reduces cell migration and induces gene expression and cell death in ovarian cancer cells

BACKGROUND: The standard treatment of ovarian cancer with chemotherapy often leads to drug resistance and relapse of the disease, and the need for development of novel therapy alternatives is obvious. The MOC31PE immunotoxin binds to the cell surface antigen EpCAM, which is expressed by the majority...

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Main Authors: Wiiger, Merete Thune, Bideli, Hemaseh, Fodstad, Øystein, Flatmark, Kjersti, Andersson, Yvonne
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3931919/
https://ncbi.nlm.nih.gov/pubmed/24528603
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1757-2215-7-23
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