PE and PS Lipids Synergistically Enhance Membrane Poration by a Peptide with Anticancer Properties

Polybia-MP1 (MP1) is a bioactive host-defense peptide with known anticancer properties. Its activity is attributed to excess serine (phosphatidylserine (PS)) on the outer leaflet of cancer cells. Recently, higher quantities of phosphatidylethanolamine (PE) were also found at these cells’ surface. We...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Biophys J
Päätekijät: Leite, Natália Bueno, Aufderhorst-Roberts, Anders, Palma, Mario Sergio, Connell, Simon D., Neto, João Ruggiero, Beales, Paul A.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: The Biophysical Society 2015
Aiheet:
Membranes
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4564682/
https://ncbi.nlm.nih.gov/pubmed/26331251
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2015.07.033
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