A Gene Gravity Model for the Evolution of Cancer Genomes: A Study of 3,000 Cancer Genomes across 9 Cancer Types

Cancer development and progression result from somatic evolution by an accumulation of genomic alterations. The effects of those alterations on the fitness of somatic cells lead to evolutionary adaptations such as increased cell proliferation, angiogenesis, and altered anticancer drug responses. How...

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Detalhes bibliográficos
Publicado no:PLoS Comput Biol
Main Authors: Cheng, Feixiong, Liu, Chuang, Lin, Chen-Ching, Zhao, Junfei, Jia, Peilin, Li, Wen-Hsiung, Zhao, Zhongming
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4564226/
https://ncbi.nlm.nih.gov/pubmed/26352260
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1004497
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