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Advances in computational approaches for prioritizing driver mutations and significantly mutated genes in cancer genomes

Cancer is often driven by the accumulation of genetic alterations, including single nucleotide variants, small insertions or deletions, gene fusions, copy-number variations, and large chromosomal rearrangements. Recent advances in next-generation sequencing technologies have helped investigators gen...

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Detalhes bibliográficos
Publicado no:Brief Bioinform
Main Authors: Cheng, Feixiong, Zhao, Junfei, Zhao, Zhongming
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4945827/
https://ncbi.nlm.nih.gov/pubmed/26307061
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bib/bbv068
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