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Advances in computational approaches for prioritizing driver mutations and significantly mutated genes in cancer genomes
Cancer is often driven by the accumulation of genetic alterations, including single nucleotide variants, small insertions or deletions, gene fusions, copy-number variations, and large chromosomal rearrangements. Recent advances in next-generation sequencing technologies have helped investigators gen...
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Publicado no: | Brief Bioinform |
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Main Authors: | , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Oxford University Press
2016
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4945827/ https://ncbi.nlm.nih.gov/pubmed/26307061 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bib/bbv068 |
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