Functional consequences of somatic mutations in cancer using protein pocket-based prioritization approach

BACKGROUND: Recently, a number of large-scale cancer genome sequencing projects have generated a large volume of somatic mutations; however, identifying the functional consequences and roles of somatic mutations in tumorigenesis remains a major challenge. Researchers have identified that protein poc...

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Autores principales: Vuong, Huy, Cheng, Feixiong, Lin, Chen-Ching, Zhao, Zhongming
Formato: Artigo
Lenguaje:Inglês
Publicado: BioMed Central 2014
Materias:
Research
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4213513/
https://ncbi.nlm.nih.gov/pubmed/25360158
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13073-014-0081-7
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