Studying Tumorigenesis through Network Evolution and Somatic Mutational Perturbations in the Cancer Interactome

Cells govern biological functions through complex biological networks. Perturbations to networks may drive cells to new phenotypic states, for example, tumorigenesis. Identifying how genetic lesions perturb molecular networks is a fundamental challenge. This study used large-scale human interactome...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Päätekijät: Cheng, Feixiong, Jia, Peilin, Wang, Quan, Lin, Chen-Ching, Li, Wen-Hsiung, Zhao, Zhongming
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Oxford University Press 2014
Aiheet:
Discoveries
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4104318/
https://ncbi.nlm.nih.gov/pubmed/24881052
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/molbev/msu167
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