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Studying Tumorigenesis through Network Evolution and Somatic Mutational Perturbations in the Cancer Interactome
Cells govern biological functions through complex biological networks. Perturbations to networks may drive cells to new phenotypic states, for example, tumorigenesis. Identifying how genetic lesions perturb molecular networks is a fundamental challenge. This study used large-scale human interactome...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4104318/ https://ncbi.nlm.nih.gov/pubmed/24881052 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/molbev/msu167 |
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