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Systematic Prioritization of Druggable Mutations in ∼5000 Genomes Across 16 Cancer Types Using a Structural Genomics-based Approach

A massive amount of somatic mutations has been cataloged in large-scale projects such as The Cancer Genome Atlas (TCGA) and the International Cancer Genome Consortium projects. The majority of the somatic mutations found in tumor genomes are neutral 'passenger' rather than damaging “driver...

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Detalhes bibliográficos
Publicado no:Mol Cell Proteomics
Main Authors: Zhao, Junfei, Cheng, Feixiong, Wang, Yuanyuan, Arteaga, Carlos L., Zhao, Zhongming
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Biochemistry and Molecular Biology 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4739678/
https://ncbi.nlm.nih.gov/pubmed/26657081
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/mcp.M115.053199
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