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Systematic Prioritization of Druggable Mutations in ∼5000 Genomes Across 16 Cancer Types Using a Structural Genomics-based Approach

A massive amount of somatic mutations has been cataloged in large-scale projects such as The Cancer Genome Atlas (TCGA) and the International Cancer Genome Consortium projects. The majority of the somatic mutations found in tumor genomes are neutral 'passenger' rather than damaging “driver...

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Bibliografski detalji
Izdano u:Mol Cell Proteomics
Glavni autori: Zhao, Junfei, Cheng, Feixiong, Wang, Yuanyuan, Arteaga, Carlos L., Zhao, Zhongming
Format: Artigo
Jezik:Inglês
Izdano: The American Society for Biochemistry and Molecular Biology 2016
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4739678/
https://ncbi.nlm.nih.gov/pubmed/26657081
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/mcp.M115.053199
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