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A network-based drug repositioning infrastructure for precision cancer medicine through targeting significantly mutated genes in the human cancer genomes

Objective Development of computational approaches and tools to effectively integrate multidomain data is urgently needed for the development of newly targeted cancer therapeutics. Methods We proposed an integrative network-based infrastructure to identify new druggable targets and anticancer indicat...

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Detalhes bibliográficos
Publicado no:J Am Med Inform Assoc
Main Authors: Cheng, Feixiong, Zhao, Junfei, Fooksa, Michaela, Zhao, Zhongming
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6370253/
https://ncbi.nlm.nih.gov/pubmed/27026610
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jamia/ocw007
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