FANCB is essential in the male germline and regulates H3K9 methylation on the sex chromosomes during meiosis

Fanconi anemia (FA) is a recessive X-linked and autosomal genetic disease associated with bone marrow failure and increased cancer, as well as severe germline defects such as hypogonadism and germ cell depletion. Although deficiencies in FA factors are commonly associated with germ cell defects, it...

Full description

Saved in:
Bibliographic Details
Published in:Hum Mol Genet
Main Authors: Kato, Yasuko, Alavattam, Kris G., Sin, Ho-Su, Meetei, Amom Ruhikanta, Pang, Qishen, Andreassen, Paul R., Namekawa, Satoshi H.
Format: Artigo
Language:Inglês
Published: Oxford University Press 2015
Subjects:
Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4550819/
https://ncbi.nlm.nih.gov/pubmed/26123487
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddv244
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items