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Elucidation of the Fanconi Anemia Protein Network in Meiosis and Its Function in the Regulation of Histone Modifications

Precise epigenetic regulation of the sex chromosomes is vital for the male germline. Here, we analyze meiosis in eight mouse models deficient for various DNA damage response (DDR) factors, including Fanconi anemia (FA) proteins. We reveal a network of FA and DDR proteins in which FA core factors FAN...

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Publicat a:Cell Rep
Autors principals: Alavattam, Kris G., Kato, Yasuko, Sin, Ho-Su, Maezawa, So, Kowalski, Ian J., Zhang, Fan, Pang, Qishen, Andreassen, Paul R., Namekawa, Satoshi H.
Format: Artigo
Idioma:Inglês
Publicat: 2016
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5095620/
https://ncbi.nlm.nih.gov/pubmed/27760317
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2016.09.073
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