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CHEK1 coordinates DNA damage signaling and meiotic progression in the male germline of mice

The continuity of life depends on mechanisms in the germline that ensure the integrity of the genome. The DNA damage response/checkpoint kinases ATM and ATR are essential signaling factors in the germline. However, it remains unknown how a downstream transducer, Checkpoint Kinase 1 (CHEK1 or CHK1),...

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Podrobná bibliografie
Vydáno v:Hum Mol Genet
Hlavní autoři: Abe, Hironori, Alavattam, Kris G, Kato, Yasuko, Castrillon, Diego H, Pang, Qishen, Andreassen, Paul R, Namekawa, Satoshi H
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2018
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6185175/
https://ncbi.nlm.nih.gov/pubmed/29360988
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddy022
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